NPM1P12

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NPM1P12 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated NPM1P12 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher NPM1P12 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NPM1P12 expression acts as an unfavorable survival marker, although some lineages such as READ and UCS show a favorable association.

KIRP, READ, and ACC are the cancer types where NPM1P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRPOSQuartileAll0.5840.808<.00194view →
READDFSTertileAll0.9060.616<.00147view →
ACCDFSTertileAll0.3660.808.00430view →
LUSCDFSQuartileII,III,IV0.3980.845.00429view →
HNSCOSTertileAll0.4990.757.00128view →
STADDFSTertileII,III,IV0.5590.809.01324view →
LIHCDFSMedianII,III,IV0.2700.378.02714view →
DLBCDFSMedianIV0.1281.000.01713view →
UCSDFSTertileIV0.8750.364.02412view →
PRADDFSQuartileAll0.9670.916.01410view →
KIRCDFSMedianIII,IV0.7160.543.0468view →
LAMLDFSMedianAll0.6540.481.0228view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

Exploration