Across TCGA pan-cancer cohorts, NPM1P12 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of NPM1P12’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NPM1P12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPM1P12 is over-expressed in tumor.
KIRC, LUAD, and COAD are the cancer types where NPM1P12 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPM1P12 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.