Across TCGA patient cohorts, NPIPB6 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,771 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NPIPB6-associated proteins across cancer lineages are UBXN7, USP39, and SMC3. Each is linked with NPIPB6 in more than 3 cancer types. Because this analysis shows association rather than direction, both NPIPB6-to-partner and partner-to-NPIPB6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB6→partner) and Y-score (partner→NPIPB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UBXN7 →	+0.462	+0.375	<.001	<.001	3	4
LSCC	USP39 →	+0.337	+0.436	<.001	<.001	3	4
GBM	SMC3 →	+0.315	+0.409	<.001	.001	3	4
HNSC	STRBP →	+0.500	+0.325	<.001	<.001	3	4
LSCC	XPO1 →	+0.229	+0.389	<.001	<.001	3	4
LSCC	RSRC1 →	+0.236	+0.389	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,771 associations by consensus.

Exploration

NPIPB6 survival (RNA) · tumor vs normal (RNA) · all NPIPB6 data types