NPIPB6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NPIPB6 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible NPIPB6-associated genes across cancer lineages are OR9Q2 and TAS2R41. Each is linked with NPIPB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPIPB6-to-partner and partner-to-NPIPB6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB6→partner) and Y-score (partner→NPIPB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCOR9Q2 →+0.020+5.643<.001.00231
LUNG_SCLCTAS2R41 →+0.135+5.029<.001.00631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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