NPIPB5

Across TCGA cell cohorts, NPIPB5 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NPIPB5-associated genes across cancer lineages are CEACAM4, CCDC105, and OR1L3. Each is linked with NPIPB5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPIPB5-to-partner and partner-to-NPIPB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CEACAM4 grouped by NPIPB5-low versus NPIPB5-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB5→partner) and Y-score (partner→NPIPB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	CEACAM4 →	+0.038	+4.652	<.001	<.001	3	1
PANCREAS	CCDC105 →	+0.008	+4.029	<.001	.007	3	1
PANCREAS	OR1L3 →	+0.008	+4.029	<.001	.007	3	1
PANCREAS	AMER3 →	+0.607	+3.862	.001	.005	3	1
PANCREAS	TRIM49D2 →	+0.012	+4.029	<.001	.007	3	1
PANCREAS	OR5G3 →	+0.026	+4.029	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

CEACAM4 by NPIPB5 expression — PANCREAS

Explore this box plot interactively →