Across TCGA patient cohorts, NPIPB4 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPIPB4-associated genes across cancer lineages are RNA5SP414, RNA5SP412, and CICP28. Each is linked with NPIPB4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPIPB4-to-partner and partner-to-NPIPB4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB4→partner) and Y-score (partner→NPIPB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP414 →	+1.275	+3.840	<.001	.007	3	1
UCEC	RNA5SP412 →	+1.510	+4.967	<.001	<.001	3	1
UCEC	CICP28 →	+0.035	+3.936	.002	.005	3	1
CESC	MTND2P18 →	+0.062	+6.837	<.001	<.001	3	1
CESC	MBD3L5 →	+0.124	+6.569	<.001	.001	3	1
CESC	RPL32P30 →	+0.732	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

NPIPB4 survival (RNA) · tumor vs normal (RNA) · all NPIPB4 data types