NPIPB3

Across TCGA cell cohorts, NPIPB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NPIPB3-associated GO terms across cancer lineages are Regulation of alternative mRNA splicing, via spliceosome, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, and Late viral transcription. Each is linked with NPIPB3 in more than 13 cancer types. Because this analysis shows association rather than direction, both NPIPB3-to-partner and partner-to-NPIPB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of alternative mRNA splicing, via spliceosome grouped by NPIPB3-low versus NPIPB3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB3→partner) and Y-score (partner→NPIPB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of alternative mRNA splicing, via spliceosome →	+0.099	+1.304	<.001	<.001	3	14
LUNG_SCLC	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.118	+0.856	<.001	<.001	3	14
STOMACH	Late viral transcription →	+0.142	+1.174	<.001	<.001	3	11
LUNG_SCLC	mRNA splice site recognition →	+0.118	+0.953	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	mRNA 5'-splice site recognition →	+0.111	+1.185	.004	<.001	2	11
UPPER_AERODIGESTIVE_TRACT	Resolution of mitotic recombination intermediates →	+0.132	+0.967	.009	.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Regulation of alternative mRNA splicing, via spliceosome by NPIPB3 expression — BONE

Explore this box plot interactively →