NPIPB1P

Across TCGA pan-cancer cohorts, NPIPB1P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated NPIPB1P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NPIPB1P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NPIPB1P expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

HNSC, UVM, and STAD are the cancer types where NPIPB1P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.418	0.199	.001	90	view →
UVM	DFS	Quartile	III,IV	0.302	0.718	.002	58	view →
STAD	DFS	Quartile	II,III,IV	0.421	0.629	.002	51	view →
ACC	OS	Tertile	III,IV	0.410	0.862	.016	34	view →
PRAD	DFS	Tertile	All	0.905	0.964	.006	30	view →
COAD	DFS	Median	III,IV	0.214	0.540	.002	27	view →
LIHC	DFS	Tertile	III,IV	0.093	0.506	<.001	27	view →
DLBC	DFS	Median	All	0.660	0.965	.001	22	view →
MESO	DFS	Tertile	IV	0.228	0.861	.010	21	view →
LGG	DFS	Median	All	0.754	0.891	<.001	18	view →
BLCA	OS	Quartile	III,IV	0.536	0.284	.017	12	view →
KIRC	DFS	Quartile	All	0.518	0.685	.025	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

NPIPB1P–HNSC (DFS)

Open the HNSC breakdown →