NPIPB1P

Across TCGA pan-cancer cohorts, NPIPB1P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NPIPB1P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where NPIPB1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPIPB1P is over-expressed in tumor, although a few such as BRCA and KIRP show the opposite, repressed pattern.

COAD, LIHC, and KIRC are the cancer types where NPIPB1P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPIPB1P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.115	.020	4	view →
LIHC	All	All	+0.055	.012	4	view →
KIRC	All	All	+0.042	.002	4	view →
BRCA	All	III,IV	−0.087	.021	2	view →
KIRP	Female	II,III,IV	−0.064	.021	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

NPIPB1P–COAD

Open the COAD breakdown →