Across TCGA patient cohorts, NPIPB15 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPIPB15-associated genes across cancer lineages are SMIM11P1, RNA5SP412, and NDUFA4P2. Each is linked with NPIPB15 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPIPB15-to-partner and partner-to-NPIPB15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB15→partner) and Y-score (partner→NPIPB15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SMIM11P1 →	+0.290	+4.979	<.001	.009	3	2
UCEC	RNA5SP412 →	+1.940	+4.552	<.001	.005	3	1
SKCM	NDUFA4P2 →	+0.221	+5.037	<.001	.009	3	1
SKCM	LINC00851 →	+0.125	+5.037	<.001	.009	3	1
BRCA	RNU6-746P →	+0.278	+8.471	<.001	.005	3	1
BRCA	RMRPP5 →	+0.124	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

NPIPB15 survival (RNA) · tumor vs normal (RNA) · all NPIPB15 data types