NPIPA2

Across TCGA patient cohorts, NPIPA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 3,997 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NPIPA2-associated proteins across cancer lineages are CCSER1_T132, EIF4EBP1, and RAI1_S1108. Each is linked with NPIPA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NPIPA2-to-partner and partner-to-NPIPA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPIPA2 versus CCSER1_T132 in LSCC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPA2→partner) and Y-score (partner→NPIPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CCSER1_T132 →	+0.904	+0.143	<.001	<.001	3	3
LSCC	EIF4EBP1 →	-0.317	-0.127	<.001	.005	3	3
PDAC	RAI1_S1108 →	+0.582	+0.129	<.001	.002	3	2
LSCC	RANBP3_T128 →	-0.426	-0.242	.009	.001	3	2
PDAC	RBBP6_T984 →	+1.278	+0.117	.006	.004	3	2
LUAD	MKI67_T1298 →	-0.925	-0.114	.008	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,997 associations by consensus.

NPIPA2 vs CCSER1_T132 — LSCC

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