NPIPA2

Across TCGA pan-cancer cohorts, NPIPA2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of NPIPA2’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where NPIPA2 RNA is repressed in tumor relative to normal tissue. In most cancer types NPIPA2 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

LUAD are the cancer types where NPIPA2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPIPA2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	−0.003	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

NPIPA2–LUAD

Open the LUAD breakdown →