NPIPA2

Across TCGA cell cohorts, NPIPA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,039 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NPIPA2-associated GO terms across cancer lineages are Intermembrane lipid transfer, Anaphase-promoting complex-dependent catabolic process, and Cilium movement. Each is linked with NPIPA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both NPIPA2-to-partner and partner-to-NPIPA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intermembrane lipid transfer grouped by NPIPA2-low versus NPIPA2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPA2→partner) and Y-score (partner→NPIPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Intermembrane lipid transfer →	+0.060	+0.898	.006	<.001	3	8
STOMACH	Anaphase-promoting complex-dependent catabolic process →	+0.071	+0.849	.007	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Cilium movement →	-0.090	-0.665	.008	.009	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.109	+0.624	.007	.004	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.094	+0.745	.007	.001	3	7
STOMACH	RNA catabolic process →	+0.047	+0.864	.005	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,039 associations by consensus.

Intermembrane lipid transfer by NPIPA2 expression — BREAST

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