NPHS1

Across TCGA cell cohorts, NPHS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,543 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NPHS1-associated GO terms across cancer lineages are Autophagy of mitochondrion, Regulation of macroautophagy, and Regulation of myoblast fusion. Each is linked with NPHS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both NPHS1-to-partner and partner-to-NPHS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagy of mitochondrion grouped by NPHS1-low versus NPHS1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPHS1→partner) and Y-score (partner→NPHS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Autophagy of mitochondrion →	+0.069	+0.244	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.075	+0.052	<.001	.001	3	7
STOMACH	Regulation of myoblast fusion →	+0.135	+0.538	<.001	.004	3	7
STOMACH	Mitochondrial electron transport, cytochrome c to oxygen →	+0.106	+0.464	<.001	.001	3	7
SOFT_TISSUE	Sensory organ morphogenesis →	-0.045	-0.395	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Primary alcohol biosynthetic process →	-0.150	-0.179	.002	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,543 associations by consensus.

Autophagy of mitochondrion by NPHS1 expression — LARGE_INTESTINE

Explore this box plot interactively →