NPHP3

Across TCGA patient cohorts, NPHP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,209 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NPHP3-associated proteins across cancer lineages are FERMT2, KANK2, and LRP1. Each is linked with NPHP3 in more than 5 cancer types. Because this analysis shows association rather than direction, both NPHP3-to-partner and partner-to-NPHP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPHP3 versus FERMT2 in BRCA, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPHP3→partner) and Y-score (partner→NPHP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FERMT2 →	+0.506	+0.462	<.001	<.001	3	6
CCRCC	KANK2 →	+0.449	+0.402	<.001	<.001	3	5
BRCA	LRP1 →	+0.433	+0.453	<.001	<.001	3	5
HNSC	MTA1 →	+0.320	+0.667	.001	<.001	3	5
BRCA	NFIC →	+0.357	+0.463	<.001	.002	3	5
HNSC	NT5C3A →	-0.496	-0.406	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,209 associations by consensus.

NPHP3 vs FERMT2 — BRCA

Explore this scatter interactively →