NPFFR2

Across TCGA patient cohorts, NPFFR2 protein abundance is significantly associated with the protein abundance of many other proteins, with 222 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NPFFR2-associated proteins across cancer lineages are GPRIN2, ANK1_S1686, and ITPRIPL2. Each is linked with NPFFR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPFFR2-to-partner and partner-to-NPFFR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPFFR2 versus GPRIN2 in LUAD, with a Pearson correlation of 0.88.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPFFR2→partner) and Y-score (partner→NPFFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GPRIN2 →	+0.453	+0.494	.001	.003	3	1
LUAD	ANK1_S1686 →	-0.840	-0.640	.003	.001	3	1
LUAD	ITPRIPL2 →	+1.609	+0.647	.002	<.001	3	1
LUAD	BCL6_S333 →	-0.850	-0.439	.004	.006	3	1
LUAD	AHNAK_S2580 →	+1.269	+0.619	.001	.002	3	1
LUAD	FBXO28 →	-0.250	-0.544	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 222 associations by consensus.

NPFFR2 vs GPRIN2 — LUAD

Explore this scatter interactively →