NPDC1

Across TCGA patient cohorts, NPDC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,611 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NPDC1-associated proteins across cancer lineages are SORBS3, SARM1, and EIF4G1. Each is linked with NPDC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NPDC1-to-partner and partner-to-NPDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPDC1 versus SORBS3 in CCRCC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPDC1→partner) and Y-score (partner→NPDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SORBS3 →	+0.456	+0.826	<.001	<.001	3	6
BRCA	SARM1 →	+0.560	+1.433	<.001	<.001	3	6
HNSC	EIF4G1 →	-0.204	-0.883	<.001	<.001	3	6
GBM	PHF2 →	+0.351	+0.787	<.001	<.001	3	6
OV	PRELP →	+1.098	+1.407	<.001	<.001	3	5
BRCA	PTPA →	+0.334	+1.535	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,611 associations by consensus.

NPDC1 vs SORBS3 — CCRCC

Explore this scatter interactively →