Across TCGA patient cohorts, NPB RNA expression is significantly associated with the go_rna of many other GO terms, with 6,831 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible NPB-associated GO terms across cancer lineages are Obsolete regulation of histone H3-K4 methylation, Regulation of spindle organization, and Axis specification. Each is linked with NPB in more than 11 cancer types. Because this analysis shows association rather than direction, both NPB-to-partner and partner-to-NPB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPB→partner) and Y-score (partner→NPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Obsolete regulation of histone H3-K4 methylation →	+0.053	+0.091	<.001	<.001	3	12
GBM	Regulation of spindle organization →	+0.034	+0.054	<.001	.002	2	12
THYM	Axis specification →	+0.034	+0.102	<.001	<.001	3	11
THYM	Obsolete histone methylation →	+0.039	+0.089	.001	<.001	3	11
ACC	Regulation of DNA replication →	+0.027	+0.050	<.001	<.001	2	12
TGCT	Regulation of protein localization to cell cortex →	+0.053	+0.111	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,831 associations by consensus.

Exploration

NPB survival (RNA) · tumor vs normal (RNA) · all NPB data types