Across TCGA patient cohorts, NOXO1 mutation is significantly associated with the RNA expression of many other genes, with 729 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOXO1-associated genes across cancer lineages are RPS29P27, RNU6-271P, and DUX4L19. Each is linked with NOXO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOXO1-to-partner and partner-to-NOXO1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOXO1→partner) and Y-score (partner→NOXO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPS29P27 →	+0.197	+7.731	<.001	.009	3	2
UCEC	RNU6-271P →	+0.240	+3.115	<.001	.007	3	2
ESCA	DUX4L19 →	+0.024	+5.450	<.001	.004	3	2
CESC	MIR410 →	+0.528	+6.342	<.001	.001	3	1
CESC	RNA5SP259 →	+0.283	+5.103	.005	.008	3	1
BRCA	OR4A17P →	+0.029	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 729 associations by consensus.

Exploration

NOXO1 survival (RNA) · tumor vs normal (RNA) · all NOXO1 data types