Across TCGA patient cohorts, NOXA1 mutation is significantly associated with the RNA expression of many other genes, with 402 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOXA1-associated genes across cancer lineages are SLC25A17, CNIH1, and CGRRF1. Each is linked with NOXA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOXA1-to-partner and partner-to-NOXA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOXA1→partner) and Y-score (partner→NOXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC25A17 →	+0.477	+3.470	.004	.003	3	1
UCEC	CNIH1 →	+0.598	+3.459	.005	.005	3	1
UCEC	CGRRF1 →	+0.506	+3.212	.003	.009	3	1
UCEC	ACD →	+0.641	+3.329	<.001	.005	3	1
UCEC	CMC2 →	+0.654	+3.387	<.001	.004	3	1
UCEC	CACTIN →	+0.448	+3.202	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 402 associations by consensus.

Exploration

NOXA1 survival (RNA) · tumor vs normal (RNA) · all NOXA1 data types