NOX3

Across TCGA patient cohorts, NOX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,254 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NOX3-associated GO terms across cancer lineages are Negative regulation of DNA biosynthetic process, Regulation of DNA biosynthetic process, and Protein acylation. Each is linked with NOX3 in more than 11 cancer types. Because this analysis shows association rather than direction, both NOX3-to-partner and partner-to-NOX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA biosynthetic process grouped by NOX3-low versus NOX3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOX3→partner) and Y-score (partner→NOX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of DNA biosynthetic process →	+0.051	+0.127	<.001	<.001	3	12
STAD	Regulation of DNA biosynthetic process →	+0.062	+0.126	<.001	<.001	3	11
STAD	Protein acylation →	+0.095	+0.208	<.001	<.001	2	12
STAD	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.088	+0.240	<.001	<.001	3	11
STAD	RNA 3'-end processing →	+0.097	+0.194	<.001	<.001	2	12
STAD	Nucleotide-excision repair →	+0.054	+0.132	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,254 associations by consensus.

Negative regulation of DNA biosynthetic process by NOX3 expression — STAD

Explore this box plot interactively →