NOX1

Across TCGA cell cohorts, NOX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,657 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NOX1-associated GO terms across cancer lineages are Radial glial cell differentiation, Cellular response to fatty acid, and Substantia nigra development. Each is linked with NOX1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NOX1-to-partner and partner-to-NOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Radial glial cell differentiation grouped by NOX1-low versus NOX1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOX1→partner) and Y-score (partner→NOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Radial glial cell differentiation →	+0.101	+0.032	.002	.001	3	4
LARGE_INTESTINE	Cellular response to fatty acid →	+0.077	+2.272	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	Substantia nigra development →	+0.071	+0.380	.001	.008	2	4
BLOOD_Myeloma	Mitochondrial gene expression →	+0.060	+0.031	.001	<.001	3	3
BLOOD_Myeloma	rRNA metabolic process →	+0.075	+0.028	<.001	.002	3	3
BLOOD_Leukemia	Cytosolic small ribosomal subunit assembly →	+0.043	+0.032	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,657 associations by consensus.

Radial glial cell differentiation by NOX1 expression — BLOOD_Leukemia

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