NOVA1

Across TCGA patient cohorts, NOVA1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,126 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NOVA1-associated genes across cancer lineages are GDAP1, NXPH3, and MAGI2. Each is linked with NOVA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both NOVA1-to-partner and partner-to-NOVA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOVA1 versus GDAP1 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOVA1→partner) and Y-score (partner→NOVA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GDAP1 →	+1.125	+1.264	<.001	<.001	3	4
BRCA	NXPH3 →	+1.169	+0.860	<.001	<.001	3	4
UCEC	MAGI2 →	+0.636	+0.674	.002	<.001	3	4
UCEC	MEIS3 →	+1.216	+0.676	<.001	.002	3	3
GBM	CTSC →	-1.063	-0.726	<.001	<.001	3	3
UCEC	AKT3 →	+1.289	+0.748	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,126 associations by consensus.

NOVA1 vs GDAP1 — BRCA

Explore this scatter interactively →