NOVA1

Across TCGA cell cohorts, NOVA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,245 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NOVA1-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Spliceosomal complex assembly, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with NOVA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both NOVA1-to-partner and partner-to-NOVA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by NOVA1-low versus NOVA1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOVA1→partner) and Y-score (partner→NOVA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of syncytium formation by plasma membrane fusion →	+0.086	+1.210	<.001	<.001	3	10
OVARY	Spliceosomal complex assembly →	+0.059	+1.051	<.001	<.001	3	9
KIDNEY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.074	+1.230	.008	.001	3	9
OVARY	DNA biosynthetic process →	+0.045	+1.464	.001	<.001	3	9
OESOPHAGUS	Cytoplasmic translation →	+0.078	+0.989	.003	.006	1	10
LUNG_NSCLC_LUSC	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.047	+1.829	.003	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,245 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by NOVA1 expression — KIDNEY

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