Across TCGA cell cohorts, NOTUM RNA expression is significantly associated with the go_rna of many other GO terms, with 2,375 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NOTUM-associated GO terms across cancer lineages are Regulation of chromatin organization, Histamine uptake, and Rac protein signal transduction. Each is linked with NOTUM in more than 5 cancer types. Because this analysis shows association rather than direction, both NOTUM-to-partner and partner-to-NOTUM results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOTUM→partner) and Y-score (partner→NOTUM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of chromatin organization →	+0.063	+2.587	.002	.004	3	6
LUNG_NSCLC_LUAD	Histamine uptake →	+0.816	+1.048	.003	.007	3	6
OESOPHAGUS	Rac protein signal transduction →	+0.076	+1.136	.005	.006	3	5
LUNG_NSCLC_LUAD	Cell division →	+0.039	+0.986	.003	.001	2	6
SKIN	Positive regulation of DNA metabolic process →	+0.048	+0.604	<.001	.009	3	5
SKIN	Epidermal cell differentiation →	-0.056	-0.384	.003	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,375 associations by consensus.

Exploration

NOTUM survival (RNA) · tumor vs normal (RNA) · all NOTUM data types