NOTCH2NLA

Across TCGA pan-cancer cohorts, NOTCH2NLA Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated NOTCH2NLA data layer compared with 24 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher NOTCH2NLA Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated NOTCH2NLA expression acts as an unfavorable survival marker.

BLCA are the cancer types where NOTCH2NLA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	0.139	0.626	.010	18	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

NOTCH2NLA–BLCA (DFS)

Open the BLCA breakdown →