NOSTRIN

Across TCGA cell cohorts, NOSTRIN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,818 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NOSTRIN-associated GO terms across cancer lineages are Double-strand break repair, Recombinational repair, and Double-strand break repair via homologous recombination. Each is linked with NOSTRIN in more than 11 cancer types. Because this analysis shows association rather than direction, both NOSTRIN-to-partner and partner-to-NOSTRIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair grouped by NOSTRIN-low versus NOSTRIN-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOSTRIN→partner) and Y-score (partner→NOSTRIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Double-strand break repair →	+0.084	+1.118	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Recombinational repair →	+0.092	+0.643	.001	.006	3	12
SOFT_TISSUE	Double-strand break repair via homologous recombination →	+0.100	+1.210	<.001	<.001	3	12
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.130	+0.895	.007	.003	3	11
BONE	Replication fork processing →	+0.135	+0.969	.005	<.001	3	11
BONE	Telomere organization →	+0.082	+0.952	.008	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,818 associations by consensus.

Double-strand break repair by NOSTRIN expression — SOFT_TISSUE

Explore this box plot interactively →