NOS3

Across TCGA patient cohorts, NOS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,424 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NOS3-associated proteins across cancer lineages are NOS3_S114, NOS3_S633, and RASIP1. Each is linked with NOS3 in more than 5 cancer types. Because this analysis shows association rather than direction, both NOS3-to-partner and partner-to-NOS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOS3 versus NOS3_S114 in LUAD, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NOS3→partner) and Y-score (partner→NOS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NOS3_S114 →	+0.663	+0.932	<.001	<.001	3	6
LUAD	NOS3_S633 →	+0.929	+0.972	.002	.002	3	6
CCRCC	RASIP1 →	+0.477	+0.752	<.001	<.001	3	5
CCRCC	BGN →	+0.946	+0.823	<.001	<.001	3	5
BRCA	CD34 →	+0.753	+0.568	.001	.001	3	5
GBM	COL18A1 →	+0.571	+0.619	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,424 associations by consensus.

NOS3 vs NOS3_S114 — LUAD

Explore this scatter interactively →