NOS2

Across TCGA patient cohorts, NOS2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,769 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NOS2-associated genes across cancer lineages are RANBP9, DPYSL3, and RTL8B. Each is linked with NOS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOS2-to-partner and partner-to-NOS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOS2 versus RANBP9 in GBM, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOS2→partner) and Y-score (partner→NOS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RANBP9 →	-0.396	-0.907	.003	.006	3	2
COAD	DPYSL3 →	-1.123	-0.828	.002	.001	3	2
COAD	RTL8B →	-0.644	-0.587	<.001	.004	3	2
COAD	TMEM150C →	-1.466	-1.103	<.001	<.001	3	2
GBM	LGALS9DP →	+0.916	+1.456	<.001	<.001	3	2
COAD	POPDC2 →	-1.078	-1.013	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,769 associations by consensus.

NOS2 vs RANBP9 — GBM

Explore this scatter interactively →