Across TCGA cell cohorts, NOS1AP mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible NOS1AP-associated genes across cancer lineages are SPINT4, OR9G4, and USP17L15. Each is linked with NOS1AP in more than 1 cancer types. Because this analysis shows association rather than direction, both NOS1AP-to-partner and partner-to-NOS1AP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOS1AP→partner) and Y-score (partner→NOS1AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SPINT4 →	+0.054	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR9G4 →	+0.049	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	USP17L15 →	+0.016	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR5M10 →	+0.019	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

NOS1AP survival (RNA) · tumor vs normal (RNA) · all NOS1AP data types