Across TCGA patient cohorts, NOP9 protein abundance is significantly associated with the RNA expression of many other genes, with 12,320 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NOP9-associated genes across cancer lineages are PARP2, CDCA4, and PRMT5. Each is linked with NOP9 in more than 7 cancer types. Because this analysis shows association rather than direction, both NOP9-to-partner and partner-to-NOP9 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP9→partner) and Y-score (partner→NOP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PARP2 →	+0.656	+0.273	.002	<.001	3	8
UCEC	CDCA4 →	+0.788	+0.262	<.001	.003	3	7
LSCC	PRMT5 →	+0.720	+0.281	<.001	<.001	3	6
HNSC	APEX1 →	+0.752	+0.148	.001	.002	3	6
OV	NGDN →	+0.558	+0.234	<.001	.008	2	7
UCEC	E2F1 →	+1.122	+0.281	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,320 associations by consensus.

Exploration

NOP9 survival (RNA) · tumor vs normal (RNA) · all NOP9 data types