Across TCGA patient cohorts, NOP9 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOP9-associated genes across cancer lineages are Caspase-7-cleavedD198, EGFR_pY1068, and eIF4E. Each is linked with NOP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOP9-to-partner and partner-to-NOP9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP9→partner) and Y-score (partner→NOP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.784	+3.341	.002	.005	3	2
UCEC	EGFR_pY1068 →	-0.339	-2.807	.001	.003	2	2
UCEC	eIF4E →	+0.189	+3.000	.040	.036	2	2
UCEC	Ku80 →	+0.290	+2.128	.005	.010	3	1
UCEC	Notch1 →	+0.147	+2.179	.017	.034	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.487	-2.102	.013	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

NOP9 survival (RNA) · tumor vs normal (RNA) · all NOP9 data types