Across TCGA cell cohorts, NOP9 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NOP9-associated genes across cancer lineages are PTH, OR4F5, and DEFB108B. Each is linked with NOP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOP9-to-partner and partner-to-NOP9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP9→partner) and Y-score (partner→NOP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PTH →	+0.049	+3.684	<.001	.006	3	1
LARGE_INTESTINE	OR4F5 →	+0.029	+3.930	<.001	.003	3	1
BLOOD_Leukemia	DEFB108B →	+0.127	+4.269	<.001	.002	3	1
BLOOD_Leukemia	CYP4A11 →	+0.029	+3.705	<.001	.007	3	1
BLOOD_Leukemia	GUCA2A →	+0.031	+4.384	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.025	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

NOP9 survival (RNA) · tumor vs normal (RNA) · all NOP9 data types