NOP58

Across TCGA patient cohorts, NOP58 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,410 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NOP58-associated proteins across cancer lineages are MCM6, MCM7, and UTP4. Each is linked with NOP58 in more than 8 cancer types. Because this analysis shows association rather than direction, both NOP58-to-partner and partner-to-NOP58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOP58 versus MCM6 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP58→partner) and Y-score (partner→NOP58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MCM6 →	+0.617	+0.514	<.001	<.001	3	9
LSCC	MCM7 →	+0.597	+0.509	<.001	<.001	3	9
UCEC	UTP4 →	+0.396	+0.625	<.001	<.001	2	9
LUAD	WDR36 →	+0.320	+0.403	<.001	<.001	3	8
PDAC	NCL_S67 →	+0.797	+0.309	<.001	.003	3	8
LSCC	ORC3 →	+0.373	+0.570	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,410 associations by consensus.

NOP58 vs MCM6 — LSCC

Explore this scatter interactively →