NOP53-AS1

Across TCGA patient cohorts, NOP53-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,860 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NOP53-AS1-associated proteins across cancer lineages are FNDC3B, THOC1, and THOC5. Each is linked with NOP53-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both NOP53-AS1-to-partner and partner-to-NOP53-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOP53-AS1 versus FNDC3B in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP53-AS1→partner) and Y-score (partner→NOP53-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FNDC3B →	-0.345	-0.366	.001	.003	3	5
LSCC	THOC1 →	+0.289	+0.564	<.001	<.001	3	4
LSCC	THOC5 →	+0.260	+0.461	<.001	<.001	3	4
LSCC	TMPO →	+0.344	+0.542	<.001	<.001	3	4
LSCC	BRD7 →	+0.211	+0.462	<.001	<.001	3	4
GBM	ORC3 →	+0.298	+0.444	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,860 associations by consensus.

NOP53-AS1 vs FNDC3B — GBM

Explore this scatter interactively →