NOP16

Across TCGA cell cohorts, NOP16 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,598 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible NOP16-associated GO terms across cancer lineages are tRNA 5'-end processing, rRNA processing, and Maturation of SSU-rRNA. Each is linked with NOP16 in more than 17 cancer types. Because this analysis shows association rather than direction, both NOP16-to-partner and partner-to-NOP16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA 5'-end processing grouped by NOP16-low versus NOP16-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOP16→partner) and Y-score (partner→NOP16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	tRNA 5'-end processing →	+0.150	+0.947	<.001	.001	3	18
BONE	rRNA processing →	+0.144	+0.982	<.001	.002	3	18
BONE	Maturation of SSU-rRNA →	+0.160	+1.103	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.143	+1.122	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Ribosome biogenesis →	+0.112	+1.220	<.001	<.001	3	18
BONE	Nucleolar large rRNA transcription by RNA polymerase I →	+0.157	+1.228	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,598 associations by consensus.

tRNA 5'-end processing by NOP16 expression — URINARY_TRACT

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