NOL9

Across TCGA patient cohorts, NOL9 mutation is significantly associated with the RNA expression of many other genes, with 2,423 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOL9-associated genes across cancer lineages are RPL36AP35, OR2AL1P, and RN7SL248P. Each is linked with NOL9 in more than 2 cancer types. Because this analysis shows association rather than direction, both NOL9-to-partner and partner-to-NOL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL36AP35 grouped by NOL9-low versus NOL9-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL9→partner) and Y-score (partner→NOL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPL36AP35 →	+0.081	+6.000	<.001	<.001	3	3
BLCA	OR2AL1P →	+0.091	+4.814	<.001	.003	3	3
SKCM	RN7SL248P →	+0.052	+4.678	<.001	.003	3	2
UCEC	ALKBH1 →	+0.454	+3.749	<.001	<.001	3	2
UCEC	CST3 →	-0.750	-3.807	<.001	<.001	3	2
UCEC	SLC35B1 →	+0.467	+2.523	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,423 associations by consensus.

RPL36AP35 by NOL9 expression — CESC

Explore this box plot interactively →