NOL9

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NOL9 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible NOL9-associated genes across cancer lineages are TEX47, CCDC182, and OR2M4. Each is linked with NOL9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOL9-to-partner and partner-to-NOL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX47 grouped by NOL9-low versus NOL9-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL9→partner) and Y-score (partner→NOL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSTEX47 →+0.413+6.357<.001<.00131
CNSCCDC182 →+0.041+4.981<.001.00831
OVARYOR2M4 →+0.070+4.700<.001.00231
OVARYPNLIPRP1 →+0.031+4.450<.001.00431
OVARYSCGB1D4 →+0.097+4.807<.001.00331
OVARYOR2H1 →+0.019+4.029.003.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

TEX47 by NOL9 expression — CNS

Box plot of TEX47 in NOL9-low vs NOL9-high samples in CNS.

Explore this box plot interactively →

Exploration