Across TCGA patient cohorts, NOL4L mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOL4L-associated genes across cancer lineages are ATM, 4E-BP1, and EGFR_pY1068. Each is linked with NOL4L in more than 1 cancer types. Because this analysis shows association rather than direction, both NOL4L-to-partner and partner-to-NOL4L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL4L→partner) and Y-score (partner→NOL4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.362	-1.247	.019	.045	3	2
UCEC	4E-BP1 →	+0.283	+3.459	.002	.005	3	2
UCEC	EGFR_pY1068 →	-0.201	-1.247	.018	.045	3	1
UCEC	ERK2 →	+0.148	+1.874	.023	.049	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.411	+1.514	.017	.015	3	1
UCEC	Ku80 →	+0.181	+1.775	.024	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

NOL4L survival (RNA) · tumor vs normal (RNA) · all NOL4L data types