NOL4

Across TCGA cell cohorts, NOL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,390 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible NOL4-associated GO terms across cancer lineages are Regulation of calcium ion transport, Chromosomal 5-methylcytosine DNA demethylation pathway, and Collagen metabolic process. Each is linked with NOL4 in more than 5 cancer types. Because this analysis shows association rather than direction, both NOL4-to-partner and partner-to-NOL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of calcium ion transport grouped by NOL4-low versus NOL4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL4→partner) and Y-score (partner→NOL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of calcium ion transport →	-0.089	-1.319	.001	.005	3	6
LUNG_SCLC	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.143	+2.970	<.001	<.001	3	6
LUNG_SCLC	Collagen metabolic process →	-0.109	-2.432	<.001	<.001	3	6
BONE	Regulation of protein maturation →	-0.174	-1.473	.002	.002	3	6
SOFT_TISSUE	Morphogenesis of an epithelium →	-0.049	-0.766	<.001	.001	3	6
SOFT_TISSUE	Mitotic cell cycle phase transition →	+0.046	+0.422	.003	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,390 associations by consensus.

Regulation of calcium ion transport by NOL4 expression — BONE

Explore this box plot interactively →