NOL3

Across TCGA patient cohorts, NOL3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,018 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NOL3-associated genes across cancer lineages are HSF4, FBXL8, and ENO2. Each is linked with NOL3 in more than 7 cancer types. Because this analysis shows association rather than direction, both NOL3-to-partner and partner-to-NOL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOL3 versus HSF4 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL3→partner) and Y-score (partner→NOL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSF4 →	+1.122	+0.520	<.001	<.001	3	8
OV	FBXL8 →	+0.643	+0.725	.001	<.001	3	6
GBM	ENO2 →	+0.825	+0.443	<.001	<.001	3	5
BRCA	SLCO5A1 →	-0.526	-0.554	.004	.001	3	5
GBM	ANGPTL4 →	+1.258	+0.512	<.001	<.001	3	5
LSCC	ATP6V0A2 →	-0.415	-0.441	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,018 associations by consensus.

NOL3 vs HSF4 — BRCA

Explore this scatter interactively →