NOL3

Across TCGA pan-cancer cohorts, NOL3 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated NOL3 data layer compared with 1 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NOL3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NOL3 expression acts as an unfavorable survival marker, although some lineages such as PCPG and READ show a favorable association.

COAD, CESC, and BLCA are the cancer types where NOL3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.510	0.829	<.001	58	view →
CESC	DFS	Tertile	II,III,IV	0.319	0.751	.013	44	view →
BLCA	OS	Median	All	0.595	0.764	.014	40	view →
LGG	OS	Median	All	0.854	0.932	<.001	39	view →
LIHC	OS	Tertile	All	0.632	0.829	<.001	34	view →
KICH	OS	Median	II,III,IV	0.611	1.000	.003	27	view →
GBM	OS	Quartile	All	0.329	0.524	.002	21	view →
LUAD	DFS	Median	II,III,IV	0.613	0.806	.001	20	view →
BRCA	DFS	Median	II,III,IV	0.866	0.909	.009	20	view →
PRAD	DFS	Tertile	All	0.822	0.931	.001	20	view →
UVM	DFS	Quartile	All	0.276	1.000	.006	19	view →
CHOL	DFS	Tertile	II,III,IV	0.114	0.685	.015	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

NOL3–COAD (OS)

Open the COAD breakdown →