Across TCGA patient cohorts, NOG protein abundance is significantly associated with the RNA expression of many other genes, with 1,258 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NOG-associated genes across cancer lineages are KCNQ5, LCT, and SLC9A5. Each is linked with NOG in more than 1 cancer types. Because this analysis shows association rather than direction, both NOG-to-partner and partner-to-NOG results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOG→partner) and Y-score (partner→NOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KCNQ5 →	+1.310	+1.370	.001	.002	3	2
LUAD	LCT →	+0.560	+0.615	.001	.006	3	2
LUAD	SLC9A5 →	+0.688	+0.888	<.001	<.001	3	2
PDAC	CEBPA →	+1.358	+1.365	.004	.002	3	2
PDAC	CEBPA-DT →	+1.515	+1.365	<.001	.002	3	2
PDAC	LINC01023 →	+1.342	+1.640	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,258 associations by consensus.

Exploration

NOG survival (RNA) · tumor vs normal (RNA) · all NOG data types