NOD1

Across TCGA cell cohorts, NOD1 RNA expression is significantly associated with the RNA expression of many other genes, with 9,160 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible NOD1-associated genes across cancer lineages are ANKRD61, PLEKHA8, and RNF216. Each is linked with NOD1 in more than 11 cancer types. Because this analysis shows association rather than direction, both NOD1-to-partner and partner-to-NOD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOD1 versus ANKRD61 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.62.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOD1→partner) and Y-score (partner→NOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	ANKRD61 →	+0.816	+0.923	<.001	<.001	3	12
KIDNEY	PLEKHA8 →	+1.031	+0.962	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	RNF216 →	+1.254	+1.102	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	USP42 →	+1.068	+1.169	<.001	<.001	3	11
OVARY	KLHL7 →	+0.890	+0.878	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	ZNF316 →	+1.230	+0.894	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,160 associations by consensus.

NOD1 vs ANKRD61 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →