NOC3L

Across TCGA cell cohorts, NOC3L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,349 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NOC3L-associated GO terms across cancer lineages are DNA replication initiation, Protein localization to condensed chromosome, and Protein localization to kinetochore. Each is linked with NOC3L in more than 17 cancer types. Because this analysis shows association rather than direction, both NOC3L-to-partner and partner-to-NOC3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by NOC3L-low versus NOC3L-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOC3L→partner) and Y-score (partner→NOC3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.162	+1.091	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.139	+1.167	.005	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.156	+1.175	.002	<.001	3	17
PANCREAS	Spindle elongation →	+0.218	+0.716	<.001	<.001	3	17
PANCREAS	Positive regulation of rRNA processing →	+0.134	+1.296	<.001	<.001	3	16
LARGE_INTESTINE	Transcription by RNA polymerase I →	+0.104	+0.820	.001	.003	2	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,349 associations by consensus.

DNA replication initiation by NOC3L expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →