NNT

Across TCGA patient cohorts, NNT protein abundance is significantly associated with the RNA expression of many other genes, with 10,367 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NNT-associated genes across cancer lineages are MRPS30, KLRD1, and TGM2. Each is linked with NNT in more than 4 cancer types. Because this analysis shows association rather than direction, both NNT-to-partner and partner-to-NNT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NNT versus MRPS30 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NNT→partner) and Y-score (partner→NNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MRPS30 →	+1.174	+0.459	<.001	.003	3	4
LSCC	KLRD1 →	-0.478	-0.326	<.001	<.001	3	4
OV	TGM2 →	-1.243	-0.413	.004	.001	3	4
PDAC	RPL29P12 →	+0.429	+0.450	<.001	.001	2	5
GBM	WAKMAR2 →	-0.577	-0.236	<.001	.006	3	4
LSCC	NNT-AS1 →	+0.627	+0.457	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,367 associations by consensus.

NNT vs MRPS30 — BRCA

Explore this scatter interactively →