NMT2

Across TCGA patient cohorts, NMT2 mutation is significantly associated with the RNA expression of many other genes, with 2,844 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NMT2-associated genes across cancer lineages are PEDS1-UBE2V1, NXNL1, and MIR6877. Each is linked with NMT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NMT2-to-partner and partner-to-NMT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PEDS1-UBE2V1 grouped by NMT2-low versus NMT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMT2→partner) and Y-score (partner→NMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PEDS1-UBE2V1 →	+0.020	+1.751	.001	<.001	3	3
CESC	NXNL1 →	+0.065	+4.961	<.001	<.001	3	2
UCEC	MIR6877 →	+0.265	+1.589	.007	.009	3	2
CESC	RN7SL248P →	+0.068	+5.263	<.001	.001	3	2
BRCA	RNU6-952P →	+0.175	+4.324	.003	.008	3	2
LUAD	RNU6-916P →	+0.338	+7.930	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,844 associations by consensus.

PEDS1-UBE2V1 by NMT2 expression — UCEC

Explore this box plot interactively →