NMRK1

Across TCGA pan-cancer cohorts, NMRK1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NMRK1 data layer compared with 25 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NMRK1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NMRK1 expression acts as an unfavorable survival marker.

LUAD, KICH, and PRAD are the cancer types where NMRK1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.237	0.812	.001	15	view →
KICH	DFS	Median	All	0.162	0.862	.014	10	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NMRK1–LUAD (OS)

Open the LUAD breakdown →