NMRK1

Across TCGA pan-cancer cohorts, NMRK1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of NMRK1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where NMRK1 RNA is repressed in tumor relative to normal tissue. In most cancer types NMRK1 is over-expressed in tumor, although a few such as LUAD and KIRP show the opposite, repressed pattern.

LUAD, KIRP, and KICH are the cancer types where NMRK1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NMRK1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−0.546	<.001	10	view →
KIRP	Female	All	−0.805	<.001	9	view →
KICH	Female	All	−1.249	<.001	8	view →
BRCA	All	III,IV	−0.567	<.001	6	view →
LIHC	All	All	−0.274	.002	4	view →
LUSC	Male	III,IV	−0.970	.010	3	view →
COAD	Female	All	−0.632	<.001	3	view →
BLCA	All	All	−0.589	.046	2	view →
PRAD	All	All	−0.271	.001	2	view →
KIRC	All	All	+0.182	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

NMRK1–LUAD

Open the LUAD breakdown →