NMRK1

Across TCGA cell cohorts, NMRK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,069 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NMRK1-associated GO terms across cancer lineages are Nicotinate metabolic process, Alkaloid metabolic process, and IMP biosynthetic process. Each is linked with NMRK1 in more than 16 cancer types. Because this analysis shows association rather than direction, both NMRK1-to-partner and partner-to-NMRK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nicotinate metabolic process grouped by NMRK1-low versus NMRK1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NMRK1→partner) and Y-score (partner→NMRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Nicotinate metabolic process →	+0.147	+1.334	<.001	<.001	3	17
OVARY	Alkaloid metabolic process →	+0.134	+1.436	<.001	<.001	3	16
LIVER	IMP biosynthetic process →	-0.139	-1.393	.004	.001	3	13
LIVER	'de novo' IMP biosynthetic process →	-0.157	-1.398	<.001	<.001	3	13
BONE	DNA replication checkpoint signaling →	-0.160	-1.316	.006	.007	3	12
BONE	Interleukin-10-mediated signaling pathway →	+0.228	+1.834	.004	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,069 associations by consensus.

Nicotinate metabolic process by NMRK1 expression — OVARY

Explore this box plot interactively →